Fenofibrate

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Q: Does Fenofibrate a cholestrol lowering drug generic for Tricor cause fatigue?
Im allergic to Lipitor and Zocor so doc put me on Fenofibrate, generic for Tricor. Even though its not a listed side effect, Im soooo sleepy all day???

A: Medical fraud alert: cholesterol lowering statin drugs save zero lives, says comprehensive research published in JAMA:

http://www.naturalnews.com/001268.html

Save your money on cholesterol lowering drugs and check your homocysteine levels. This is the leading cause of heart attack and stroke. 6.3umol/L is the ideal level:

http://www.squidoo.com/homocysteine-hcy

Side effects of fenofibrate includes fatigue..not all side effects are listed on the pamphlet and only 1% of side effects are reported…one side effect listed..which means someone (who knows how many) reported it..is myocardial infarct (heart attack) O_o

http://www.drugs.com/sfx/fenofibrate-side-effects.html

Q: Is there a known side effect between fenofibrate and gingko biloba?
- If you can offer links, I will appreciate it.

A: just know about ginkgo low quality or doses of more than 120mg will leave u with high ginkgolick acid levels leading to problems and its a blood thinner so e fish or flax seed oil blood thinners and anticoagulants can cause a clotting problem 4 sum with ginkgo

Q: Has anyone ever noticed any memory lost after taking fenofibrate?
I don’t know if it is my imagination or if the drug might have an effect on my memory. I take it for colesterol

A: HI Ruth – I wasn’t familiar with this medication so I looked it up for you. While it doesn’t mention memory loss it does mention dizziness and lightheadedness which I would imagine woulkd lead to a sence of memory loss. Have you experienced either of those symptoms?

If it were me I would ask my Dr about it. Especially if the memory loss is pronounced. It could be a sign of another problem. If it’s just a matter of feeling scatter brained it very well could be secondary to the above side effects. My antidepression meds did that to me at first. I have now gotten used to them but at first I was really having trouble remembering basic things like appointments, where I left my car keys etc. It was getting frustrating!

Here is the link where I got the info – http://www.nlm.nih.gov/medlineplus/druginfo/meds/a601052.html

Hope that helps a bit!

Q: Has anyone ever heard of Prevacid or Fenofibrate causing memory loss?

A: Prevacid, no. Fenofibrate, yes.
Prevacid and other acid blockers can prevent the proper digestion of food and any tablets ingested, but that’s about all the side effects don’t list.
Fenofibrate and other Cholesterol blockers (including Statins) on the other hand CAN cause memory loss and multiple older people prescribed Cholesterol blockers are also diagnosed with Alzheimer’s shortly after. The reason for this is that they block the cholesterol production in all parts of your body, including your brain. Your brain produces cholesterol in order to aid the myelin sheaths that coat the neurons and help nerve function, plus cholesterol is used in the formation of synapses. When this cholesterol production in the brain is stopped, the nerves can’t function as well, the synapses aren’t as strong, and the basic functions of the brain can’t work as well.
One of the funniest things about this is that Statins have cognitive problems listed as the second-most common side effect. www.rxlist.com even lists “amnesia” under the serious side effects.

One of the funniest reports I saw was a doctor with decades of experience that was prescribed a cholesterol-lowering drug and after only 6 weeks, he was found wandering around, not knowing where he was or anyone around him (including his wife). He got off it for a while, felt better, then got back on and it happened again. That’s when he did more research about it and became an advocate for the Statins causing memory problems. His website is listed below.

Q: Does the medication TriCor (fenofibrate) for high triglycerides increase your risk of colon cancer?
I think I remember reading about this link, but a quick literature review did not turn anything up. Thanks for your help.

A: It appears that the studies have some mixed results. Some of the studies are actually leaning towards that TriCor is a help in some treatments of some cancers. see this link:

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1475879

although you may not be a candidate for endometrial cancer, still the study is interesting.
Here is another study in which fenofibrate is one of a combination of drugs being used in treatment for cancer:

http://www.clinicaltrials.gov/ct/show/NCT00357500;jsessionid=31132CAB8FBA197D58CE44F2D90B8848?order=7

On the other hand, here is a link to another view:

http://www.drugs.com/cons/Fenofibrate_Systemic.html

Q: When is the best time to take fenofibrate? My pharm says at night, doctor w/food.?
I took it at night as recommended by my pharmacist and my blood work came back with HIGHER triglycerides than B4!

A: did your doctor say anything about still taking the pill or what you should do.when you got the pills was there information for you to read about the pills.if the doctor did not tell you to stopp taking the pill or gave you another prescrption,than that will mean that the dr.wants you to stay on that pill?he does know what is best for you,and will not give you something to cause harm to you.it might be awhile longer for the pill to work properly?do not worry? stay calm,stress is not good for you?

Q: What are the following drugs for? Fenofibrate. L-Arginine. Actifolate.?

A: Don’t you know how to search the internet?

L-arginine is an over the counter amino acid supplement. They say taking it is good for wound healing and muscle repair.

Fenofibrate is a prescription used to treat high cholesterol and high triglyceride levels.

Actifolate is an over the counter folate supplement. It contains folate a B vitamin.

Q: does Fenofibrate cause a negative pregnancy test?

A: it shouldn’t have any effect on the production of beta hcg or it’s detection in urine or blood
you better check the urine early morning if negative repeat within 3 days to 1 week again early morning
if still not sure see your dr for a blood test
fenofibrate is contraindicated during pregnancy and breastfeeding
ideally you should get a pregnancy test prior to starting this drug and avoid getting pregnant while on it just to be on the safe side
good luck sweetie

Q: Is Fenofibrate as dangerous to take as Statin drugs?
I have been taking lovastatin for about 6 years and other statins prior to that. I recently developed a polyneuropathy condition that may have been caused by this (not certain). I have recently read some very bad things about statins and how they can have incredibly bad side effects. I got off the statin drug about 1-2 weeks ago. I was also on 54mg of Fenofibrate which I am still taking. I read that this should not be taken with a statin drug, but my GP had put me on these none the less. 20 mg lovastatin and 54 mg Fenofibrate. Is the Fenofibrate as dangerous as statin drugs? Can they mutate mitochondria like some of the papers out there say statins do? Do they reduce CoQ10 like statins do? Should i drop this med as well?
Mitochondrial Mutations and Statins is discussed at:

http://www.spacedoc.net/mitochondrial_mutations_statins.html

A: You generally should not take the fibrate class of medication with statins, as it increases the risk of rhabdomyolysis, however, even when these drugs are combined, this risk is extremely small. As such, they can be used together – the fibrates provide benefits that statins do not. Notably, they can reduce circulating triglyceride levels, which statins do not do. Caution needs to be used, and occasional liver enzyme monitoring is a good idea, however there needs to be an evaluation on the risk of this effect versus the benefits – so the combo is typically used in patients with severe cardiovascular disease, major risk factors like diabetes or extremely poor lipid profiles.

I would not look in the direction of statins for polyneuropathy. The number of things that can cause this is absolutely enormous, and diabetes (which occurs

I cannot find sources saying that statins can mutate mitochondria (or mitochondrial DNA). I did find some papers discussing statins being problematic in patients with mitochondrial disorders – but these disorders are very rare.

Alone, the fibrates are rather safe drugs.

Any changes with your medication, you must consult with the doctor who prescribed that medication. Bring your concerns to them, and work with them to make decisions. Altering a medication regimen without medical training is a recipe for disaster.

Edit: That site is NOT a good source of information at all. I would regard any information on it as false unless substantiated by reliable, outside sources.

Q: Does Fenofibrate cause polyneuropathy?
I was recently diagnosed with Polyneuropathy which currently manifests itself as tingling and numbness in all my toes on both feet. I’ve been taking lovastatin, fenofibrate, hydrochlorothiazide and metoprolol (for blood pressure). About a week ago I stopped taking the lovastatin which I’ve been taking for over 6 years. I have also been feeling tired and I’ve had IBS for 3 years. My sugar level is 109. I’ve read that statins can cause polyneuropathy. Can Fenofibrate do this as well? It looks like we are slowly being killed with all these drugs.

A: There are case reports of fenofibrate causing paresthesias, which you describe in your question. These account for <1% of adverse events, according to Lexi-comp (a drug database I use).

One of the biggest causes of polyneuropathy (as manifested by paresthesias) is longstanding diabetes (not saying this is your case).

Things that control it:

-Tight blood glucose control. Some of my patients could tell their blood sugar is high based on the tingling in their hands/feet

-Drugs like Neurontin (gabapentin), Lyrica (pregabalin) and amitriptyline have a place in treating pain associated with neuropathy.

Best of luck to you.

By the way,

The primary adverse events of fenofibrate are as follows:

>10%: Hepatic: Liver function tests increased (dose related; 3% to 13%)

1% to 10%:

Central nervous system: Headache (3%)

Gastrointestinal: Abdominal pain (5%), constipation (2%), nausea (2%)

Neuromuscular & skeletal: Back pain (3%), CPK increased (3%)

Respiratory: Respiratory disorder (6%), rhinitis (2%)

Q: Is it OK to take both Lovastatin and Fenofibrate together?
I am currently taking both Lovastatin and Fenofibrate together for cholesterol as set up by my GP.
I recently read somewhere on internet that these two drugs SHOULD NOT be taken together…(haven’t found it again or i’d post it here). I’m taking 20 mg of Lovastatin a day and 54 mg of Fenofibrate a day. I recently started getting a tingling numbness in my toes and will soon be checked out by a neurologist for Peripheral Neuropathy. I don’t know if drugs are causing it. I had blood tests and GP said he didn’t see a cause for it in the results. My blood sugar is around 109 but other numbers and ratios are good.

Is taking Lovastatin and Fenofibrate a problem? Should I stop taking both?

A: it is a very dangerous combination that should be avoided . because it can cause what is known by rhabdomyolysis ( muscle destruction and extreme muscle pain ). in very rare cases they are given together but the patient must be extremely monitored.
you need to talk to your doctor and let him know about this combination.

Q: what is the medication fenofibrate prescribed for?

A: belongs to class of meds called fibrates, reduce your cholesterol and your LDL , your bad cholesterol

Q: how long should I be taking Lipicard 160 mg prescribed two months back to lower my triglyceride level?
I was prescribed Lipicard 160 mg (fenofibrate) on my triglyceride recording of 340. I have been taking the medicine for two months. How long should I be taking this medicine as it is said to have hepatic side effects.

A: fenofibrate is a good prescription medicine typically your doctor will check cholesterol profile anywhere from 6-12 weeks after starting the medicine, at the same time your liver profile will be checked too. as for long term, start dieting and exercise and try to lower the dose gradually while you keep up with cholesterol profile checks every 6-12 weeks, if they stay low with diet and exercise then you could probably eventually discontinue the drug. Otherwise I agree omaga 3 or fish oil 1000 mg 2-3 times a day is a good supplement not alternate. take vitamin e 400 units daily if you take fish oil. good luck

Q: What does “serum turbid” mean, when I am measuring Tri-glycerides? does it affect my reading? how do I improve
I went for a blood test for my lipid profile. I had a
tri glyceride 403 mg/dl ( Serum turbid).
cholesterol 177mg/dl
HDL 28
LDL 97
VLDL 81

My doc put me on fenofibrate for 3 months.
What does serum turbid mean? How does it affect my readings? My earlier tests did not have any such terms. Please explain and also let me know how to improve on my cholesterol.

A: When the serum is turbid, it usually means there is a high concentration of fatty globules dissolved in it, so that it is not clear. Your HDL’s are low, so that tells me you are not very physically active. Your VLDL’s are high, so you have been eating a diet that is either very high in fat, or you have a genetic predispostion to increased cholesterol. Your total cholesterol count is a total of all three—206, which is high, but not all that high. The low HDL’s and the very high triglycerides are troubling, and may indicate a devloping diabetes problem, or impaired functioning of liver and pancreas. You need to discuss this more thoroughly with your physician, so that you are able to understand, and develop a treatment plan that is right for you.

Q: Which of the followong is a cholesterol-lowering drug that works by inhibiting an enzyme called HMG-CoA?
Cholestyramine resin (Questran)
Doxazosin )Cardura)
Fenofibrate (Tricor)
Fluvastatin (Lescol)

A: The fluvastatin.

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